Sorry, your browser is not compatible with some of the content on this website. Please update to a newer browser to view this website.

Bio and Body Identical Hormones

Body identical hormone therapy can help to improve and balance mood swings, low libido, anxiety, poor memory or “brain fog” as well as have a positive impact on sleep quality, bone strength, energy levels and skin ageing. I specialize in the prescription of  Body identical hormones to manage symptoms and restore optimal health. Since every woman is unique, I want to give women a choice of treatment options.

What are Bio and Body identical hormones ?

Both Bio as well as Body identical hormones have the identical chemical structure as the hormone molecules produced by our own body. Some of the conventional HRT that is commonly prescribed is extracted from the urine of pregnant mares (e.g. Premarin). These equine hormones, though produced “naturally” are not identical to those that occur and are made by our own body. Equine hormones as well as other synthetic conjugated hormones mimic hormonal activity but are essentially foreign to our bodies and can cause side effects along the way. The effect Body identical hormones are more consistent with our physiological biochemistry and therefore if balanced correctly side effects should be minimal or non-existent.

Our body makes three different forms of Estrogen: Estrone (E1), Estradiol (E2) and Estriol (E3). Estradiol (E2) is the most potent Estrogen and even though it only makes up 10% of the total Estrogen in a woman’s body, it is the most important Estrogen during the reproductive years and it is made in large quantities during pregnancy.  As ovarian function declines in a woman reaching the menopause, Estrogen levels fall dramatically and this can be associated with hot flushes, an increased cardiovascular risk and loss of bone density. Studies have shown that Estrogen therapy does have a cardio-protective and bone protective effect, particularly in women younger than 60 years of age. Estrogen therapy does not increase the breast cancer risk.

Progesterone is a hormone that during the reproductive years prepares the lining of the womb for the implantation of a fertilised egg and it also helps maintain the embryo during pregnancy. Low levels of progesterone are associated with amenorrhea,  fertility problems, post-natal depression and pre-menstrual syndrome (PMS).  Progesterone production slows down earlier than Estrogen production during the peri-menopausal years from about the age of 40. This can result in irregular cycles, heavy periods, headaches and mood swings.

The British Menopause Society states in their Handbook: “Studies have demonstrated that micronised progesterone apppears to have a better safety profile when compared with synthetic progestogens and may result in a different safety profile. ” (page 86, 2017 Edition). Studies suggest that with micronised progesterone there is a lower risk of breast cancer, a lower risk of cardiovascular disease and a lower risk for venous thromboembolism (blood clots), compared with synthetic progesterones.

Bio-Identical Hormones

Bio-identical Hormones as well as most Body-identical hormones are derived from converting a substance called Diosgenin, which is sourced from Mexican yams. The main difference between Bio and Body identical hormones is that Bio-identical hormones are compounded (mixed) according to a doctor’s personalized prescription in a licensed specialist pharmacy.

Bio-identical hormones are much more expensive than the NHS standard prescription fee. Compounded hormones and medicines were not tested in a standardized pharmaceutical trials. Even though I have trained in prescribing Bio-Identical hormones, I always recommend licenced and standardized HRT as a first line treatment. 

Body-Identical Hormones

Body-identical hormones are licensed, branded, standardized products and their efficacy and safety have been tested and proven in pharmaceutical trials. Body-identical hormone products are plant derived and manufactured by a pharmaceutical company. They are often available on prescription from your GP and with this prescription you can get them from your local Pharmacy. There is currently no Testosterone hormone replacement preparation available on the NHS which is licensed for women. Doctors who want to prescribe Testosterone for women currently have to prescribe products designed for men off-license and adjust the dose to suit the physiological level of the female body.

How are Bio and Body identical hormones administered?

  • Bio-identical HRT: creams, lozenges, capsules
  • Body-identical HRT: gels, patches, capsules,  vaginal pessaries, creams and rings.